Recover Better
Hurt Less
Precision OrthoCryo® uses targeted cold therapy to quiet the nerves that cause post-surgical pain.
Cold That Quiets Pain.
Not Just Masks It.
Cryoneurolysis uses precisely targeted cold to temporarily interrupt the pain signals from the nerves around your surgical site — before and after your procedure. Unlike opioids, it treats the source of pain directly, without affecting your ability to think, move, or heal.
The iovera° device delivers a small, controlled freeze to specific nerves in a quick in-office visit. The effect lasts up to 90 days — long enough to get you through the hardest part of recovery.
Before Surgery
A quick in-office treatment targets the nerves around your surgical site. You arrive, get treated, and go home the same day.
During Recovery
Pain signals are quieted for up to 90 days — reducing your need for opioids and helping you engage more fully in physical therapy.
Back to Your Life
Patients move sooner, sleep better, and report higher satisfaction with their recovery compared to standard pain management alone.
Real Results.
Backed by Research.
From peer-reviewed studies: Dasa V, et al. Knee. 2016 · Plessl D, et al. J Am Acad Orthop Surg. 2020
iovera° vs. Standard Care
See how targeted cryoneurolysis compares to conventional post-operative pain management across the outcomes that matter most.
| Outcome | iovera° Cryotherapy Precision OrthoCryo® | Standard Care Opioids / PT alone |
|---|---|---|
| Post-op opioid use | ↓ 45% reduction Dasa et al., Knee 2016 | High — routine prescribing Dependency risk |
| Hospital length of stay | 0.8 days shorter Plessl et al., JAAOS 2020 | 2.5 days average Higher bed utilization |
| Pain relief duration | Up to 90 days Single pre-op treatment | Days to weeks Requires ongoing medication |
| Functional recovery (KOOS) | 2× better scores Weeks 6 & 12 post-op | Baseline improvement Standard PT trajectory |
| Systemic side effects | None Localized, reversible | Nausea, sedation, constipation Common with opioids |
| HCAHPS pain scores | Significantly improved Better patient satisfaction | Variable Pain often undertreated |
| Addiction / dependency risk | None No opioid exposure | Clinically significant ~6% develop dependency |
| Procedure setting | In-office, same day No downtime | Inpatient / pharmacy Ongoing management |
Sources: Dasa V, et al. Knee. 2016; Plessl D, et al. J Am Acad Orthop Surg. 2020
Hear From Patients Like You
"Before my total knee replacement, a friend recommended cryotherapy to help manage post-surgical pain. Everyone says knee replacement is no walk in the park, but honestly, my pain was very manageable from day one. I was able to control it using only Tylenol and an anti-inflammatory medication. I know every patient's experience is different, but I truly believe the cryotherapy made a significant difference in both my comfort and recovery. It helped me stay motivated during rehab, push through physical therapy, and get back to my normal activities much faster than I expected. I would highly recommend it!"
Published Clinical Outcomes
65%
Opioid reduction
Dasa et al. 2016
68%
Less pain at rest
Post-TKA cohort
0.8 days
Shorter hospital stay
Plessl et al. 2020
100%
No added complications
Across all studies
Published Clinical Results
From peer-reviewed studies · Dasa et al. 2016 · Plessl et al. 2020
65%
Opioid reduction
Dasa et al. 2016
68%
Less pain at rest
Post-TKA cohort
0.8 days
Shorter hospital stay
Plessl et al. 2020
100%
No added complications
Across all studies
Scheduled for Surgery?
You May Be a Candidate.
Cryoneurolysis is available for patients undergoing common orthopedic procedures. If you're concerned about post-operative pain or want to reduce your reliance on opioids during recovery, ask your surgeon about Precision OrthoCryo.
Bill Ives, PA-C
Retired U.S. Army Major · Combat Veteran · Orthopedic PA
Ten years as a U.S. Air Force medic — including a Desert Storm deployment — followed by Army combat tours in Iraq and Afghanistan, PA school, and a career in orthopedic surgery shaped a single conviction: patients deserve targeted pain relief without opioid dependency. That conviction became Precision OrthoCryo®.
Your CJR-X Partner for
Value-Based Joint Replacement.
CJR-X makes bundled payment accountability mandatory for most U.S. hospitals starting January 2028. Precision OrthoCryo delivers preoperative pain optimization, outcomes tracking, and a turnkey service line — zero capital, operational in 60 days.
Ready for a Better Recovery?
Find out if cryoneurolysis is right for your upcoming surgery, or locate a Precision OrthoCryo provider near you.
Talk to your surgeon about whether Precision OrthoCryo is right for your procedure.